Les découvertes scientifiques du GEFLUC Paris IDF

Les découvertes scientifiques du GEFLUC Paris IDF

Articles publiés par année de parution

Une découverte scientifique est une avancée remarquable dans le domaine des sciences. Elle prend officiellement le terme de découverte scientifique quand elle est reconnue par une communauté d’experts ou de chercheurs dans le domaine.

Ces articles sont des découvertes scientifiques de chercheuses et chercheurs qui ont bénéficié d’une subvention des Entreprises contre le cancer, GEFLUC Paris IDF.

Cécile Haumaitre, 2023, « Acinar-to-Ductal Metaplasia (ADM)_ On the Road to Pancreatic Intraepithelial Neoplasia (PanIN) and Pancreatic Cancer », International Journal of Molecular Sciences

Clément Linger, 2023, « Volumetric and Simultaneous Photoacoustic and Ultrasound Imaging With a Conventional Linear Array in a Multiview Scanning Scheme », IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

Delphine Garnier, 2023, « Extracellular Vesicles in Chronic Lymphocytic Leukemia_ Tumor Microenvironment Messengers as a Basis for New Targeted Therapies_ », MDPI

Karim Taouis, 2023, « WWOX binds MERIT40 and modulates its function in homologous recombination, implications in breast cancer », Nature

Lucas Blasquez, 2023, « Ebselen oxide and derivatives are new allosteric HER2 inhibitors for HER2-positive cancers », Molecular Oncology

Mélina L. Heuzé, 2023, « The ER tether VAPA is required for proper cell motility and anchors ER-PM contact sites to focal adhesions », BioRxiv

Patrycja Pawlikowska, 2023, « FANCA deficiency promotes leukaemic progression by allowing the emergence of cells carrying oncogenic driver mutations », Nature

Emilie Elvira-Matelot, 2022, « NF-κB signaling controls H3K9me3 levels at intronic LINE-1 and hematopoietic stem cell genes in cis », The Journal of Experimental Medicine

Lubka T Roumenina, 2022, « C1q+ macrophages_ passengers or drivers of cancer progression », Trends in Cancer

Maimouna D. N’Gadjaga, 2022, « Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways », Journal of Biological Chemistry

Manon Watzky, 2022, « Hexokinase 2 is a transcriptional target and a positive modulator of AHR signalling », Nucleic Acids Research, 2022, Vol. 50, No. 10

Marc Pocard, 2022, « Magnetic Compression of Tumor Spheroids Increases Cell Proliferation In Vitro and Cancer Progression In Vivo », MDPI

Maurice Zaoui, 2022, « Adipocytes secretome from normal and tumor breast favor breast cancer invasion by metabolic reprogramming », Clinical and Translational Oncology

Pénélope Darnat, 2022, « Cortical Cyclin A controls spindle orientation during asymmetric cell divisions in Drosophila », Nature Communications

Théotim Lucas 2022, « Calibrated Photoacoustic Spectrometer Based on a Conventional Imaging System for In Vitro Characterization of Contrast Agents », MDPI

Victoria Cluzet, 2022, « Estradiol promotes cell survival and induces Greb1 expression in granulosa cell tumors of the ovary through an ERα-dependent mechanism », The Journal of Pathology

Sébastien Jauliac, 2022, « The NFAT3_RERG Complex in Luminal Breast Cancers Is Required to Inhibit Cell Invasion and May Be Correlated With an Absence of Axillary Lymph Nodes Colonization », Frontiers in Oncology

Ahlem Jebali, 2021,« RICTOR Affects Melanoma Tumorigenesis and Its Resistance to Targeted Therapy », MDPI 2021 - Endocrine-Related Cancer] Role of circadian rhythm disorders on EMT and tumour–immune interactions in endocrine-related cancers-1

Camille Faure, 2021, « Allosteric inhibition of HER2 by Moesin-mimicking compounds targets HER2-positive cancers and brain metastases », American Association for Cancer research

Camille Faure, 2021, « Allosteric Inhibition of HER2 by Moesin-Mimicking Compounds Targets HER2-Positive Cancers and Brain Metastases », Cancer Research

Communiqué de Presse, 2021, Inserm, The Journal of Pathology

Evans Quilichini, 2021, « Insights into the etiology and physiopathology of MODY5_HNF1B pancreatic phenotype with a mouse model of the human disease », Wiley Online Library

Hervé Acloque, 2021, « Effets des altérations du rythme circadien sur l’évolution du cancer du sein », Medecine Science Review

Nathalie Magne, 2021, « PAK3 is a key signature gene of the glioma proneural subtype and affects its proliferation, differentiation and growth », Cellular Oncology

Théotim Lucas, 2021,« High-Contrast and -Resolution 3-D Ultrasonography with a Clinical Linear Transducer Array Scanned in a Rotate-Translate Geometry », MDPI

Jean-Marc Ricort, 2020, « Protein Kinase D1 (PKD1) Is a New Functional Non-Genomic Target of Bisphenol A in Breast Cancer Cells », Frontiers in Pharmacology

Benoit Maffei, 2020,« Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells », The EMBO Journal

Clémence Carron, 2020, « The regulatory proteins DSCR6 and Ezh2 oppositely regulate Stat3 transcriptional activity in mesoderm patterning during Xenopus development », Journal of Biological Chemistry

Franck Toledo, 2020, « Mechanisms Generating Cancer Genome Complexity_ Back to the Future », MDPI

Franck Toledo, 2020, « Germline mutation of MDM4, a major p53 regulator, in a familial syndrome of defective telomere maintenance », Science Advances

Hervé Acloque, 2020, « Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice », Nature Communications

Patrycja Pawlikowska, 2020; « Microphthalmia transcription factor expression contributes to bone marrow failure in Fanconi anemia », The Journal of Clinical Investigation

Marie-Line Puiffe, 2020, « IL4I1 Accelerates the Expansion of Effector CD8+ T Cells at the Expense of Memory Precursors by Increasing the Threshold of T-Cell Activation », Frontiers in Immunology

Pauline Tétu, 2020, « FGF2 Induces Resistance to Nilotinib through MAPK Pathway Activation in KIT Mutated Melanoma », MDPI

Victoria Cluzet, 2020, « Aberrant granulosa cell-fate related to inactivated p53_Rb signaling contributes to granulosa cell tumors and to FOXL2 downregulation in the mouse ovary », Springer Nature

Adèle Mangelinck, 2019, « MT2A is an early predictive biomarker of response to chemotherapy and a potential therapeutic target in osteosarcoma », Nature, Scientific Reports

Cyril Carvalho, 2019, « Glucocorticoids delay RAF-induced senescence promoted by EGR1 », The Company of Biologists

Elise Chapiro, 2019, « Genetic characterization of B-cell prolymphocytic leukemia_ a prognostic model involving MYC and TP53 », The American Society of Hematology

Eva Benaboua, 2019, « Insulin receptor isoform A favors tumor progression in human hepatocellular carcinoma by increasing stem_progenitor cell features », Elsevier

Evans Quilichini, 2019, « Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis », Cellular and Molecular Gastroenterology and Hepatology

Maeva Elzaiat, 2019, « High-throughput Exploration of the Network Dependent on AKT1 in Mouse Ovarian Granulosa Cells », The American Society for Biochemistry and Molecular Biology, Inc.

Sarah Moitrier, 2019, « Local light-activation of the Src oncoprotein in an epithelial monolayer promotes collective extrusion », Communications Physics

Maurice Zaoui, 2019, « Breast-Associated Adipocytes Secretome Induce Fatty Acid Uptake and Invasiveness in Breast Cancer Cells via CD36 Independently of Body Mass Index, Menopausal Status and Mammary Density », MDPI

Florian Bonin, 2018, « VOPP1 promotes breast tumorigenesis by interacting with the tumor suppressor WWOX », BMC Biology

Franck Toledo, 2018, « The Guardian of the Genome Revisited_ p53 Downregulates Genes Required for Telomere Maintenance, DNA Repair, and Centromere Structure », MDPI

Guillaume Duclos, 2018, « Controlling Confinement and Topology to Study Collective Cell Behaviors », Methods in Molecular Biology, Chapter 28

Jan Philipp Ramspott, 2018, « Emerging Role of IL-4eInduced Gene 1 as a Prognostic Biomarker Affecting the Local T-Cell Response in Human Cutaneous Melanoma », Journal of Investigative Dermatology

Sarah Moitrier, 2018, « Collective stresses drive competition between monolayers of normal and Ras-transformed cells† », Royal Society of Chemistry

Anna Sawicka, 2017, « Micropipette force probe to quantify single-cell force generation_ application to T-cell activation », Molecular Biology of the Cell (MBoC)2017 Beyer et al Methods

Lloyd Bod, 2017, « IL-4−Induced Gene 1 _ A Negative Immune Checkpoint Controlling B cell Differentiation and Activation », The Journal of Immunology

Nathalie Ferrand, 2017, « WISP1_CCN4 inhibits adipocyte differentiation through repression of PPARγ activity », Scientific Reports, Nature

Nicolas Ortonne, 2017, « PDE4D promotes FAK-mediated cell invasion in BRAF-mutated melanoma », Nature

Robin Tranchant, 2017, « Hétérogénéité moléculaire des mésothéliomes pleuraux malins », Bulletin du Cancer

Sophie Beyer, 2017, « Tandem Affinity Purifi cation Approach Coupled to Mass Spectrometry to Identify Post-translational Modifi cations of Histones Associated with Chromatin-Binding Proteins », Methods in Molecular Biology, Chapter 2

Andrelou F Vallarelli, 2016, « TERT promoter mutations in melanoma render TERT expression dependent on MAPK pathway activation », Oncotarget2016 10634-161780-2-PB

Anne Ramat, 2016, « Escargot and Scratch regulate neural commitment by antagonizing Notch activity in Drosophila sensory organs », The Company of Biologists

Christèle Desbois-Mouthon, 2016, « Heregulin-1ß and HER3 in hepatocellular carcinoma_ status and regulation by insulin », Journal of Experimental & Clinical Cancer Research

Robin Tranchant, 2016, « Co-occurring Mutations of Tumor Suppressor Genes, LATS2 and NF2, in Malignant Pleural Mesothelioma », Clinical Cancer Research

Valentine Battisti, 2016, « Canonical Wnt signalling regulates nuclear export of Setdb1 during skeletal muscle terminal differentiation », Nature

Valentine Battisti, 2016, « Unexpected Distinct Roles of the Related Histone H3 Lysine 9 Methyltransferases G9a and G9a-Like Protein in Myoblasts », Elsevier

Véronique Joliot, 2016, « Identification of MyoD Interactome Using Tandem Affinity Purification Coupled to Mass Spectrometry », Jove

Cécile Haumaitre, 2015, « Implication of epigenetics in pancreas development and disease », Elsevier2015 BPRCEM

Chiara Mozzetta, 2015, « Sound of silence_ the properties and functions of repressive Lys methyltransferases », Nature Reviews

Chiara Mozzetta, 2014, « The Histone H3 Lysine 9 Methyltransferases G9a and GLP Regulate Polycomb Repressive Complex 2-Mediated Gene Silencing », Cell Press

Véronique Joliot, 2014, « The SWI_SNF Subunit_Tumor Suppressor BAF47_INI1 Is Essential in Cell Cycle Arrest upon Skeletal Muscle Terminal Differentiation », PLOS One

Hamza Chettouh, 2013, « Mitogenic Insulin Receptor-A Is Overexpressed in Human Hepatocellular Carcinoma due to EGFR-Mediated Dysregulation of RNA Splicing Factors », Cancer Research

Michèle Sabbah, 2011, « CCN5, a Novel Transcriptional Repressor of the Transforming Growth Factor Signaling Pathway », American Society for Microbiology